Bismuth Nanoparticles are also known as nanocrystal, nanopowder, or nanodots. These nanoparticles are the nontoxic and high surface area magnetic non-structured particles. The Bismuth nanoparticles have a variety of applications. They are harmless to human life. These particles serve as the industrial lubricant additive, heat transfer medium in a nuclear reactor, an alloy agent in metallurgy, and a contrast agent in the medical image and cancer radiotherapy. Apart from this, the bismuth nanoparticles have several other uses such as it is used in fire detectors, electric fuses, and in solders. However, when these particles are alloyed with tin or cadmium, then these particles are used as extinguishers. On the other hand, the industries of paint and cosmetics also use bismuth nanoparticles. In the field of glazes, plumbing, and ceramics these particles are used as the substitute of lead. Additionally, the bismuth nanoparticles are also useable in medication at a large level. So, these particles play a pivotal role because of its matchless uses.